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Monthly Archives: December 2010
Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project
Abstract We systematically generated large-scale data sets to improve genome annotation for the nematode Caenorhabditis elegans, a key model organism. These data sets include transcriptome profiling across a developmental time course, genome-wide identification of transcription factor–binding sites, and maps of chromatin … Continue reading
RSEQtools: A modular framework to analyze RNA-Seq data using compact, anonymized data summaries
Abstract Summary: The advent of next-generation sequencing for functional genomics has given rise to quantities of sequence information that are often so large that they are difficult to handle. Moreover, sequence reads from a specific individual can contain sufficient information … Continue reading
