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Functional Big-Data Genomics
Abstract High-throughput genomic sequencing is characterized by large diverse datasets and numerous analysis methods. It is normal for an individual bioinformatician to work with thousands of data files and employ hundreds of distinct computations during the course of a single … Continue reading
Biocaml: The OCaml Bioinformatics Library
Abstract Biology is an increasingly computational discipline due to rapid advances in experimental techniques, especially DNA sequencing, that are generating data at unprecedented rates. The computational techniques needed range from the complex (.e.g algorithms, distributed computing) to the simple (e.g. … Continue reading
Managing and Analyzing Big-Data in Genomics
Abstract Biology is an increasingly computational discipline. Rapid advances in experimental techniques, especially DNA sequencing, are generating data at exponentially increasing rates. Aside from the algorithmic challenges this poses, researchers must manage large volumes and innumerable varieties of data, run … Continue reading
logit – a simple tool to date-stamp files into a log directory
http://github.com/agarwal/logit
Toward Interactive Statistical Modeling
Abstract When solving machine learning problems, there is currently little automated support for easily experimenting with alternative statistical models or solution strategies. This is because this activity often requires expertise from several different ï¬elds (e.g., statistics, optimization, linear algebra), and … Continue reading
Automating Mathematical Program Transformations
Abstract Mathematical programs (MPs) are a class of constrained optimization problems that include linear, mixed-integer, and disjunctive programs. Strategies for solving MPs rely heavily on various transformations between these subclasses, but most are not automated because MP theory does not … Continue reading